10 years ago, Pilsen was European Capital of Culture (EcoC), 10 years ago I started my position in the ECoC selection panel. At a celebration in Pilsen, I reflected in my key note speech about future culture policy options of cites. What remains? This is a frequent question to European Capitals of Culture. I argue that while good evaluation of the past is great learning, we need to focus on main transformation areas in culture policy. Cities dispose of some key features helping us to cope with the challenges of the 21st century and to better use related opportunities. A key element is the power of cities and citizens in relation-building. Cities are important providers of the cultures of relationships. Cities are built in context. They never stand alone. It is in their intrinsic interest (to survive) to have good relations, internally to organise the urban lifestyle of permanent (forced, volunteer) interaction and community building, externally to provide the citizens with the required resources from near and far. These specific features should orient updated city culture policies. I argue that we need a clear focus on internationalisation strategies, urban-rural cooperation, public spaces and social cohesion. All are interaction areas under substantial pressure in 21st century societies. Cities can provide models to turn this conflict zones into spaces of cooperation and good relations while furthering democracy. Congratulations to the Pilsen team for this great event and initiative. Adela, Ivana and Michaela you were perfect hosts!